Miranda-COPD Study Sponsor and Protocol Number: AstraZeneca (D9180C00012) Specialty: Pulmonology Type: Investigational Drug Inclusion: Age 40+ Former smoker with 10 pack year history 2 moderate or 1 severe COPD exacerbation in the last 12 monthsICS/LABA/LAMA dual or triple therapy Exclusion: Asthma